The Deadly Chemistry That Made Life Interesting - YouTube Die tödliche Chemie, die das Leben interessant machte - YouTube Η θανάσιμη χημεία που έκανε τη ζωή ενδιαφέρουσα - YouTube The Deadly Chemistry That Made Life Interesting - YouTube La química mortal que hizo interesante la vida - YouTube La chimie mortelle qui a rendu la vie intéressante - YouTube A halálos kémia, amely érdekessé tette az életet - YouTube La chimica mortale che ha reso la vita interessante - YouTube 人生を面白くした致命的な化学 - YouTube 삶을 흥미롭게 만든 치명적인 화학 - YouTube Mirtina chemija, dėl kurios gyvenimas tapo įdomus - "YouTube De dodelijke chemie die het leven interessant maakte - YouTube Śmiercionośna chemia, która uczyniła życie interesującym - YouTube A química mortal que tornou a vida interessante - YouTube Смертоносная химия, которая сделала жизнь интересной - YouTube Hayatı İlginç Kılan Ölümcül Kimya - YouTube Смертельна хімія, яка зробила життя цікавим - YouTube 让生活变得有趣的致命化学 - YouTube 讓生活變得有趣的致命化學 - YouTube

- Hey, Smart People. Joe here. - Hey, Smart People. Joe here. - やあ、賢い人たち。ジョーです。

There's been life on this planet There's been life on this planet Já houve vida neste planeta

for at least 3.7 billion years. durante pelo menos 3,7 mil milhões de anos.

But for most of that time,

life was really, really, really boring. a vida era muito, muito, muito aborrecida.

It was all just simple little cells squirming Tudo não passava de simples células a contorcerem-se

around in water. na água.

No cute furry things. Nada de coisas fofas e peludas.

No weird bugs. Não há insectos estranhos.

No trees. (alarm buzzes)

Just microscopic blobs blobbing. Just microscopic blobs blobbing. Apenas bolhas microscópicas a borbulhar.

And then, around half a billion years ago, E depois, há cerca de meio bilião de anos,

after about 3 billion years of boring, após cerca de 3 mil milhões de anos de aborrecimento,

something amazing happened.

Life exploded into all kinds of interestingness. A vida explodiu em todos os tipos de interesse.

Worms.

Trilobites.

A five-eyed sea-creature called Opabinia. Uma criatura marinha com cinco olhos chamada Opabinia. П'ятиока морська істота на ім'я Опабінія.

And countless other complex lifeforms. E inúmeras outras formas de vida complexas. І незліченна кількість інших складних форм життя.

I mean, out of nowhere, life on Earth began a new chapter. Demək istəyirəm ki, heç bir yerdən, Yerdəki həyat yeni bir fəsil başladı. Quer dizer, do nada, a vida na Terra começou um novo capítulo. Я маю на увазі, що з нізвідки життя на Землі почало новий розділ.

It's hard to put time scales like these into perspective. É difícil colocar escalas de tempo como estas em perspetiva.

If the history of life were a single day, Se a história da vida fosse um único dia,

and life began at midnight, e a vida começou à meia-noite,

life didn't get interesting until around 10:30 PM. A vida só se tornou interessante por volta das 22:30h.

And that explosion of interestingness took place Et cette explosion d'intérêt a eu lieu E essa explosão de interesse teve lugar

in less than an hour on our history-of-life clock. em menos de uma hora no nosso relógio da história da vida.

But why didn't life just stay boring? Mas porque é que a vida não se manteve aborrecida?

What changed? O que é que mudou?

When we typically think of natural selection, Quando pensamos tipicamente na seleção natural,

the process by which organisms evolve, change, and adapt, o processo pelo qual os organismos evoluem, mudam e se adaptam,

we think of this gradual thing pensamos nesta coisa gradual

that happens over huge time periods. que ocorre em grandes períodos de tempo.

But that's not what happened here. Mas não foi isso que aconteceu aqui.

The ancestors of all life's complex creatures showed up, Os antepassados de todas as criaturas complexas da vida apareceram,

the variety of life on Earth exploded like that. a variedade de vida na Terra explodiu assim.

And that's because, right before that explosion,

a new kind of chemistry entered the equation.

A chemistry that, in excess, could spell certain death,

but in the right doses was about to set the stage

for life as we know it today.

Understanding why this happened,

and what this new chemistry enabled,

might even tell us something important about

what life might look like elsewhere.

(gentle music)

When life first showed up on Earth,

the air was most likely made of nitrogen, plus some CO2,

water vapor, and small amounts of other gases.

There was hardly any oxygen.

So if you went back in time 3.7 billion years,

you'd immediately suffocate and die.

So early life was anaerobic: It didn't breathe oxygen.

Instead, it got all its energy

from minerals dissolved into the ocean.

Cells just sat there while seawater passed

through their membranes, absorbing dissolved compounds.

Those compounds interacted with other molecules in the cells

and set off chain reactions.

Electrons hopping from one molecule to the other,

molecules joining together or split apart,

and in the end, creating a famous molecule known as ATP.

ATP exists in every single cell

in every single living thing,

it's life's universal way

of storing energy cells need to function.

But this lazy anaerobic way to get energy

only produced enough ATP to take care of basic housekeeping.

Early boring lifeforms didn't have spare energy

they could use to grow bigger.

Now, since these early cells were basically nutrient traps,

it might seem like they should work like fishing nets,

the bigger the net, the bigger the catch.

But for cells, it actually doesn't work out that way.

As cells get bigger, it's true that they have

more surface area to let in nutrients,

but they also have much, much more volume.

And that volume grows faster than surface area.

So a bigger single cell can't catch

enough stuff to feed all its volume.

This meant that early anaerobic lifeforms were

pretty much doomed to stay small and boring.

Even today, organisms that don't use oxygen

to make energy are almost all

just single, microscopic cells.

But, around 2.4 billion years ago,

something happened that completely changed

the course of life.

Some of these simple cells learned a new trick.

A whole new way of making ATP, and lots of it.

They started doing photosynthesis.

Eating light and air to power your cells is pretty cool.

And it creates a waste product, oxygen gas.

Over the next few hundred million years,

early photosynthetic cells just churned this stuff out.

Oxygen levels went from almost nothing

to about 10% the amount of oxygen in our air today,

and the planet drastically changed, in a semi-deadly way.

According to one leading theory,

oxygen reacted with greenhouse gasses,

changing the makeup of the atmosphere

so that it stopped trapping as much heat.

That would explain why Earth's temperature plunged

1.9 billion years ago,

so much that it froze over from the poles to the tropics.

Oxygen started out as catastrophic.

But Earth's oxygen-rich atmosphere is also

the reason that we're around today.

By using oxygen, your cells metabolize food

completely differently than those early lifeforms.

You get way more ATP for every bit

of organic matter that you consume.

It's about 10 times more efficient

than those original anaerobic ways of creating ATP.

And life needed all of that energy to grow

and get more interesting.

So this period, called the Great Oxygenation,

often gets the credit for paving the way for complex life:

As the story goes, it created air that could be breathed,

and that air enabled life to get complex,

and the rest was history.

But that's not the full story.

Chances are, we would never have gotten

this incredible array of lifeforms living on every inch

of this planet if it weren't for a couple freak accidents,

and a crucial give-and-take between biology and some rocks.

So remember when Earth froze over after oxygen showed up?

Well, volcanoes pumped some greenhouse gases

back into the atmosphere,

and things gradually warmed up enough to thaw.

And then something happened between two microscopic cells

that, well, it changed everything:

At least 1.7 billion years ago,

one cell just gulped up another one.

The swallowed cell started living inside the other one.

It evolved into what we call the mitochondrion-

- [Announcer] The powerhouse of the cell!

(thunder crackles)

- An organelle whose main job is

to create ATP for its host cell.

Up until this point, all cells were prokaryotes:

simple bags of stuff without any division

of labor going on inside.

But suddenly, in this leap of evolution, that changed.

Some biologists think evolution

basically would have stalled if this hadn't happened,

because every single animal

and plant on Earth is made of eukaryotic cells,

complex cells whose ancestors were born

in that moment when one cell swallowed another

and took it hostage and squeezed all the energy out of it.

Meanwhile, the general blueprint

of single-celled organisms has hardly changed

in 3 billion years.

Prokaryotes didn't gradually morph into eukaryotes

through a bunch of gradual evolutionary steps.

(alarm buzzes)

This one evolutionary leap, basically a freak accident,

changed the entire course of life's history.

And this kind of freak event happened twice.

Around 1.25 billion years ago,

a eukaryotic cell cannibalized another cell.

This time, it was a photosynthesizing bacterium

that got gulped up.

Over time, that evolved into a chloroplast,

the organelle that does photosynthesis.

Today, every single plant has cells like this,

full of chloroplasts and mitochondria.

Forget gradual change.

Without sudden, huge leaps in evolution,

plants and animals just don't exist. plants and animals just don't exist.

But what's weird is, even though, 1.25 billion years ago,

life already had the building blocks it needed

to create all sorts of complex plants and animals,

we didn't get this immediate burst

of interestingness at all.

In fact, some biologists call this time period,

from 1.8 billion years ago

to 800 million years ago, the "Boring Billion."

Evolution was happening, but really slowly.

Because even though photosynthesizing bacteria

were pumping out a bunch of oxygen,

it wasn't enough to support big, breathing animals.

The problem was, the amount of oxygen bacteria could make

likely depended on something else: phosphorus.

No one gives phosphorus any love. Ніхто не дає фосфору ніякої любові.

Cells use phosphorus to make membranes, proteins, DNA.

Basically, no phosphorus, no cells.

And at the time, Earth had lots of phosphorus,

but it was mostly locked up in the crust,

not dissolved in the ocean, where the bacteria were.

Prokaryotes were starved for P,

so their population likely stalled

for hundreds of millions of years.

But over time, a series of ice ages created glaciers

that scraped up the ground,

freeing up some of the locked-up phosphorus.

Wind and rain wore down the continents,

washing a bunch of that phosphorus into the oceans.

Life finally had all the ingredients

that it needed to get interesting:

It had eukaryotic cells,

which would become the building blocks of complex organisms.

It had photosynthesizing cells pumping out oxygen.

And it had enough phosphorus to sustain all of this.

So, after around 3 billion years of life on Earth, Отже, після приблизно 3 мільярдів років життя на Землі,

evolution wasn't on hold anymore. еволюція більше не стояла на паузі.

Natural selection could do its thing,

and life exploded into zillions of different forms

in just hundreds of millions of years.

I know that sounds like a long time,

but as major evolutionary changes go,

it's basically overnight.

So how does life get complex?

Well, first, cells start living together,

and they split up tasks: some digesting the food,

others providing structure, some just for mating.

Eventually, some of these cell communes evolved

into simple animals.

And over time, animals kept getting bigger and weirder.

Some were shaped like ribbons and tubes.

They stopped staying in one place,

and started taking advantage of those big stores of ATP

to seek out other organisms for fuel.

Harvesting and hunting brought in more fuel

for their bodies, which let them get even bigger.

Organisms also got more complex as they evolved new tactics

for finding dinner and avoiding becoming dinner.

They grew heads and tails and armors and spines.

I mean, natural selection went wild.

While none of this would have happened

without oxygen in our atmosphere,

an oxygen-rich planet comes with a few risks.

I mean, quite possibly the first thing it did

to our planet was freeze it into an Earth-sized snowball,

which we already talked about.

That was not great.

But on the flip side, oxygen also gave us fire.

Nothing would burn on Earth without oxygen in the air,

and the more oxygen there is, the more flammable things are.

But when it comes to oxygen and life,

the big catch is that oxygen is toxic.

We all breathe air that's around 21% oxygen.

But if people are exposed

to higher concentrations of oxygen,

they can actually be poisoned.

'Cause the thing about oxygen is that it's super reactive.

To put it chemistry specific, it has two unpaired electrons,

which really want to form chemical bonds.

So oxygen yanks electrons off other molecules

whenever it gets the chance.

This is known as oxidizing,

and it's how we get things like rust.

If oxygen steals electrons from molecules in our bodies,

it creates unstable molecules called

free radicals that can damage cells.

Our bodies have some natural defenses against this.

Antioxidants are molecules in lots of fruits and vegetables

that can easily give up electrons to free radicals

and keep them from reacting with cells and doing damage.

But these defenses can get overwhelmed

if the oxygen concentration is too high.

And even if antioxidants aren't overwhelmed,

some free radicals still slip through,

slowly damaging our cells year after year.

Some scientists think we have oxygen to blame

for part of aging and age-related diseases.

In a way, oxygen itself both gives life and takes it away.

So, sure, the Great Oxygenation was pretty great.

But oxygen gas was not this elusive elixir of life.

It was a double-edged sword.

And it took much more than a burst of oxygen

to give us life as we know it.

The story of life on earth isn't just a story about biology.

It's a story about geology

and chemistry overlapping with biology.

We needed a planet that could support simple lifeforms

for billions of years.

We needed some of those lifeforms

to fill our air with oxygen.

And we needed some well-timed freak accidents

to create the building blocks of complex life.

Then we needed geological conditions to line up just right

before life could get interesting at all.

So, complex life might not be

the inevitable endpoint of generations of evolution.

You might need more than a planet

with just the right ingredients

at just the right distance from a star.

It kinda suggests that even if we do one day find

another planet with simple lifeforms,

that life may never get interesting or intelligent.

So, as we live on our planet covered

in incredible plants and animals, breathing this deadly,

flammable gas that also somehow gives us life,

the fact that we're here at all

might be even more remarkable than we thought.

Stay curious.

And as always, thank you for sticking

around to the end of the video,

and thank you to everyone who supports this show on Patreon.

We literally could not do this without you.

Much like oxygen, you give us life

and you keep these videos complex,

because summarizing the entire history of complex life

into one episode is not an easy task.

It takes us a lot of work to research

and put these videos together.

The support of our patrons is essential

to keep making videos the way

that we know that you love them.

So support at any level will help us keep doing that.

You can find out more information down in the description.

Go ahead and clicky-click the button

and we will see you in the next video.

Explanation of demo.

(crew member laughs)

Okay. Thank you.

I just read what it says.

(Joe grunts)