×

We use cookies to help make LingQ better. By visiting the site, you agree to our cookie policy.


image

Aspirin May Halt Tumor Growth

Aspirin May Halt Tumor Growth

Aspirin may be a useful weapon in the fight against cancer, according to a new study. Lead researcher Helen Arthur with the Institute of Human Genetics at Newcastle University in England says she and her colleagues explored a biological process called angiogenesis that stimulates blood vessels to grow. "It's important, for example, in a healing wound. If you cut yourself, you need new vessels to grow to help to repair the tissue." Arthur and her research team found that aspirin can block the formation of blood vessels that feed tumor growth. In test-tube studies researchers analyzed the effects of various doses of aspirin on cells that line the inside of human blood vessels. "We found at a very low dose of aspirin, similar to the kinds of doses that are used therapeutically, it had a strong inhibitory effect on the way cells forms tubes [vessels] in the angiogenesis assay." Arthur cautions patients not to take aspirin to prevent or cure cancer. She says aspirin in large doses over an extended period of time is toxic and can lead to severe stomach bleeding and death. "We need to develop safe delivery methods for getting aspirin in." Arthur says doing so could lead to the production of new cancer fighting drugs.

The aspirin study is published in the October issue of the journal of the Federation of American Societies for Experimental Biology.


Aspirin May Halt Tumor Growth

Aspirin may be a useful weapon in the fight against cancer, according to a new study. Lead researcher Helen Arthur with the Institute of Human Genetics at Newcastle University in England says she and her colleagues explored a biological process called angiogenesis that stimulates blood vessels to grow. "It's important, for example, in a healing wound. If you cut yourself, you need new vessels to grow to help to repair the tissue." Arthur and her research team found that aspirin can block the formation of blood vessels that feed tumor growth. アーサーと彼女の研究チームは、アスピリンが腫瘍の成長を促進する血管の形成を阻止できることを発見しました。 In test-tube studies researchers analyzed the effects of various doses of aspirin on cells that line the inside of human blood vessels. 試験管の研究では、研究者は、人間の血管の内側を覆う細胞に対するさまざまな用量のアスピリンの効果を分析しました。 "We found at a very low dose of aspirin, similar to the kinds of doses that are used therapeutically, it had a strong inhibitory effect on the way cells forms tubes [vessels] in the angiogenesis assay." 「私たちは、治療に使用される種類の用量と同様に、非常に低用量のアスピリンで、血管新生アッセイで細胞が管[血管]を形成する方法に強い阻害効果があることを発見しました。」 Arthur cautions patients not to take aspirin to prevent or cure cancer. アーサーは、癌を予防または治療するためにアスピリンを服用しないように患者に警告しています。 She says aspirin in large doses over an extended period of time is toxic and can lead to severe stomach bleeding and death. 彼女は、長期間にわたる大量のアスピリンは有毒であり、重度の胃の出血と死につながる可能性があると言います。 "We need to develop safe delivery methods for getting aspirin in." 「私たちはアスピリンを摂取するための安全な送達方法を開発する必要があります。」 Arthur says doing so could lead to the production of new cancer fighting drugs. アーサーはそうすることは新しい癌と戦う薬の生産につながるかもしれないと言います。

The aspirin study is published in the October issue of the journal of the Federation of American Societies for Experimental Biology. アスピリンの研究は、米国実験生物学会連合のジャーナルの10月号に掲載されています。